The human body is made up of 60 trillion cells, each one of which has genome in its core, containing all the genetic information essential for survival of the individual. The genome is composed of four bases, A (adenine), T (thymine), G (guanine), and C (cytosine), which form approximately three billion DNA base pairs of A-T and C-G.
What is Gene Expression?
Gene expression is the process by which the information from a gene is converted into structures and functions of a cell, and eventually protein is produced based on gene information. Therefore, if the quantity of mRNA (messenger RNA) which is a source to produce protein is measured, we can understand which gene is expressed and the rate/amount of the gene expression. We can also know what has occurred in the human body.
Methods for quantifying gene expression
There are mainly 3 methods to quantify gene expression:
Our body maintains homeostasis by the cells with a certain function bonding together and forming tissues and the tissues so formed working properly. Impairment of the tissue function or runaway cells that are not controlled properly within the tissue can cause cancer and other illness. This means that the functions of cells are controlled within the tissues for the purpose of maintaining homeostasis of the individual.
This control of the cells takes place in the form of which part of genome containing full genetic information is used in what way. A part of genome (DNA) is transcribed into RNA (“transcription”) and then translated into protein based on the sequence information of the transcribed mRNA.
This protein is the one that performs the functions. The process of this reading and translation of a series of genetic information, which is called central dogma involving DNA>RNA>protein, is not necessarily disorderly performed on the genome and it is strictly controlled by time. This maintains the functions of tissues and homeostasis of individuals.
The solution for the gene analysis equipment of CKD
As for each DNA analysis equipment introduced here, the highly precise control technology for DNA samples and reagents as well as so-called fluid control technology are set to be one of the key technologies.
Another feature is that there is no risk of a contaminant entering a medical analytical instrument. Besides, the equipment has high durability that ensures the reliability of the instrument despite their compact size which is also a great feature.
CKD offers components that incorporate the state-of-art technologies in the medical equipment to achieve the best performance from gene analysis equipment.